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Transoral resection of pharyngeal cancer: Summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6–7, 2011, Arlington, Virginia

Identifieur interne : 000789 ( Main/Exploration ); précédent : 000788; suivant : 000790

Transoral resection of pharyngeal cancer: Summary of a National Cancer Institute Head and Neck Cancer Steering Committee Clinical Trials Planning Meeting, November 6–7, 2011, Arlington, Virginia

Auteurs : David J. Adelstein [États-Unis] ; John A. Ridge [États-Unis] ; David M. Brizel [États-Unis] ; F. Christopher Holsinger [États-Unis] ; Bruce H. Haughey [États-Unis] ; Brian O'Sullivan [Canada] ; Eric M. Genden [États-Unis] ; Jonathan J. Beitler [Géorgie (pays)] ; Gregory S. Weinstein [États-Unis] ; Harry Quon [États-Unis] ; Douglas B. Chepeha [États-Unis] ; Robert L. Ferris [États-Unis] ; Randal S. Weber [États-Unis] ; Benjamin Movsas [États-Unis] ; John Waldron [Canada] ; Val Lowe [États-Unis] ; Scott Ramsey [États-Unis] ; Judith Manola [États-Unis] ; Bevan Yueh [États-Unis] ; Thomas E. Carey [États-Unis] ; Justin E. Bekelman [États-Unis] ; Andre A. Konski [États-Unis] ; Eric Moore [États-Unis] ; Arlene Forastiere [États-Unis] ; David E. Schuller [États-Unis] ; Jean Lynn [États-Unis] ; Claudio Dansky Ullmann [États-Unis]

Source :

RBID : ISTEX:8E103754F5B37B62ED993CF663A82B3FC1F50062

Descripteurs français

English descriptors

Abstract

Recent advances now permit resection of many pharyngeal tumors through the open mouth, an approach that can greatly reduce the morbidity of surgical exposure. These transoral techniques are being rapidly adopted by the surgical community and hold considerable promise. On November 6–7, 2011, the National Cancer Institute sponsored a Clinical Trials Planning Meeting to address how to further investigate the use of transoral surgery, both in the good prognosis human papillomavirus (HPV)–initiated oropharyngeal cancers, and in those with HPV‐unrelated disease. The proceedings of this meeting are summarized. © 2012 Wiley Periodicals, Inc. Head Neck, 2012

Url:
DOI: 10.1002/hed.23136


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<term>Ipsilateral</term>
<term>Laryngoscope</term>
<term>Laser</term>
<term>Late rtog grade</term>
<term>Late toxicities</term>
<term>Late toxicity</term>
<term>Lateralized</term>
<term>Lesion</term>
<term>Life outcomes</term>
<term>Locoregional</term>
<term>Locoregional control</term>
<term>Lymph</term>
<term>Lymph nodes</term>
<term>Mayo clinic</term>
<term>Metastasis</term>
<term>Microsurgery</term>
<term>Modality</term>
<term>Morbidity</term>
<term>Multicenter</term>
<term>National cancer institute</term>
<term>Neck cancer</term>
<term>Neck cancer patients</term>
<term>Neck cancers</term>
<term>Neck dissection</term>
<term>Neck surgery</term>
<term>Nodal</term>
<term>Node</term>
<term>Noninferiority</term>
<term>Noninferiority trials</term>
<term>Nonsurgical</term>
<term>Nonsurgical management</term>
<term>Nonsurgical treatment</term>
<term>Normal tissue</term>
<term>Oncol</term>
<term>Oncologic</term>
<term>Oncologic results</term>
<term>Opscc</term>
<term>Oral cavity</term>
<term>Oropharyngeal</term>
<term>Oropharyngeal cancer</term>
<term>Oropharyngeal cancers</term>
<term>Oropharyngeal carcinoma</term>
<term>Oropharynx</term>
<term>Oropharynx cancer</term>
<term>Otolaryngol</term>
<term>Otolaryngol head neck surg</term>
<term>Papillomavirus</term>
<term>Pathologic</term>
<term>Pathologic findings</term>
<term>Perineural invasion</term>
<term>Pharyngeal</term>
<term>Pharyngeal cancer</term>
<term>Pharynx</term>
<term>Phys</term>
<term>Policy makers</term>
<term>Positive margin</term>
<term>Positive margins</term>
<term>Posterior pharyngeal wall</term>
<term>Postoperative</term>
<term>Postoperative adjuvant therapy</term>
<term>Postoperative irradiation</term>
<term>Postoperative radiation</term>
<term>Postoperative radiation therapy</term>
<term>Pretreatment</term>
<term>Pretreatment imaging</term>
<term>Primary modality</term>
<term>Primary site</term>
<term>Princess margaret hospital</term>
<term>Prognosis</term>
<term>Prospective study</term>
<term>Radiat</term>
<term>Radiat oncol biol phys</term>
<term>Radiat oncol biol phys eisbruch</term>
<term>Radiation therapy</term>
<term>Radiother</term>
<term>Radiother oncol</term>
<term>Radiotherapy</term>
<term>Randomized</term>
<term>Randomized trials</term>
<term>Recurrence</term>
<term>Regimen</term>
<term>Resection</term>
<term>Retropharyngeal</term>
<term>Retropharyngeal lymph nodes</term>
<term>Retropharyngeal nodes</term>
<term>Rtog</term>
<term>Selective neck dissection</term>
<term>Shoulder function</term>
<term>Smoking history</term>
<term>Squamous</term>
<term>Squamous cell carcinoma</term>
<term>Subclinical disease</term>
<term>Surg</term>
<term>Surgery</term>
<term>Surgical</term>
<term>Surgical exposure</term>
<term>Surgical margins</term>
<term>Surgical resection</term>
<term>Systemic chemotherapy</term>
<term>Target volume</term>
<term>Therapy</term>
<term>Tongue base</term>
<term>Tor</term>
<term>Toxicity</term>
<term>Transoral</term>
<term>Transoral laser microsurgery</term>
<term>Transoral resection</term>
<term>Transoral resections</term>
<term>Transoral surgery</term>
<term>Trial design</term>
<term>Uninvolved neck</term>
<term>Untreated</term>
</keywords>
<keywords scheme="Teeft" xml:lang="en">
<term>Adelstein</term>
<term>Adjuvant</term>
<term>Adjuvant therapy</term>
<term>Anderson cancer center</term>
<term>Arch otolaryngol head neck surg</term>
<term>Biol</term>
<term>Biomarkers</term>
<term>Cancer</term>
<term>Cancer institute</term>
<term>Carcinoma</term>
<term>Caregiver burden</term>
<term>Cell cancer</term>
<term>Cell carcinoma</term>
<term>Central review</term>
<term>Cetuximab</term>
<term>Chemoradiation</term>
<term>Chemotherapy</term>
<term>Cisplatin</term>
<term>Clin</term>
<term>Clin oncol</term>
<term>Clinical trial</term>
<term>Clinical trials</term>
<term>Cohort</term>
<term>Comparative effectiveness research</term>
<term>Comparative view</term>
<term>Complete response</term>
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<term>Composite endpoints</term>
<term>Concurrent chemoradiation</term>
<term>Concurrent chemotherapy</term>
<term>Concurrent cisplatin</term>
<term>Cooperative groups</term>
<term>Correlative</term>
<term>December</term>
<term>Definitive radiotherapy</term>
<term>Disease control</term>
<term>Dissection</term>
<term>Dos</term>
<term>Dysfunction</term>
<term>Dysphagia</term>
<term>Effective interventions</term>
<term>Elective</term>
<term>Elective irradiation</term>
<term>Endpoint</term>
<term>Engl</term>
<term>Extracapsular</term>
<term>Extracapsular spread</term>
<term>Functional imaging</term>
<term>Functional outcome</term>
<term>Functional outcomes</term>
<term>Gastrostomy</term>
<term>Gastrostomy tube dependence</term>
<term>Good prognosis</term>
<term>Haughey</term>
<term>Head december</term>
<term>Head neck</term>
<term>Health states</term>
<term>High risk</term>
<term>Human papillomavirus</term>
<term>Imaging</term>
<term>Impairment</term>
<term>Imrt</term>
<term>Induction chemotherapy</term>
<term>Ipsilateral</term>
<term>Laryngoscope</term>
<term>Laser</term>
<term>Late rtog grade</term>
<term>Late toxicities</term>
<term>Late toxicity</term>
<term>Lateralized</term>
<term>Lesion</term>
<term>Life outcomes</term>
<term>Locoregional</term>
<term>Locoregional control</term>
<term>Lymph</term>
<term>Lymph nodes</term>
<term>Mayo clinic</term>
<term>Metastasis</term>
<term>Microsurgery</term>
<term>Modality</term>
<term>Morbidity</term>
<term>Multicenter</term>
<term>National cancer institute</term>
<term>Neck cancer</term>
<term>Neck cancer patients</term>
<term>Neck cancers</term>
<term>Neck dissection</term>
<term>Neck surgery</term>
<term>Nodal</term>
<term>Node</term>
<term>Noninferiority</term>
<term>Noninferiority trials</term>
<term>Nonsurgical</term>
<term>Nonsurgical management</term>
<term>Nonsurgical treatment</term>
<term>Normal tissue</term>
<term>Oncol</term>
<term>Oncologic</term>
<term>Oncologic results</term>
<term>Opscc</term>
<term>Oral cavity</term>
<term>Oropharyngeal</term>
<term>Oropharyngeal cancer</term>
<term>Oropharyngeal cancers</term>
<term>Oropharyngeal carcinoma</term>
<term>Oropharynx</term>
<term>Oropharynx cancer</term>
<term>Otolaryngol</term>
<term>Otolaryngol head neck surg</term>
<term>Papillomavirus</term>
<term>Pathologic</term>
<term>Pathologic findings</term>
<term>Perineural invasion</term>
<term>Pharyngeal</term>
<term>Pharyngeal cancer</term>
<term>Pharynx</term>
<term>Phys</term>
<term>Policy makers</term>
<term>Positive margin</term>
<term>Positive margins</term>
<term>Posterior pharyngeal wall</term>
<term>Postoperative</term>
<term>Postoperative adjuvant therapy</term>
<term>Postoperative irradiation</term>
<term>Postoperative radiation</term>
<term>Postoperative radiation therapy</term>
<term>Pretreatment</term>
<term>Pretreatment imaging</term>
<term>Primary modality</term>
<term>Primary site</term>
<term>Princess margaret hospital</term>
<term>Prognosis</term>
<term>Prospective study</term>
<term>Radiat</term>
<term>Radiat oncol biol phys</term>
<term>Radiat oncol biol phys eisbruch</term>
<term>Radiation therapy</term>
<term>Radiother</term>
<term>Radiother oncol</term>
<term>Radiotherapy</term>
<term>Randomized</term>
<term>Randomized trials</term>
<term>Recurrence</term>
<term>Regimen</term>
<term>Resection</term>
<term>Retropharyngeal</term>
<term>Retropharyngeal lymph nodes</term>
<term>Retropharyngeal nodes</term>
<term>Rtog</term>
<term>Selective neck dissection</term>
<term>Shoulder function</term>
<term>Smoking history</term>
<term>Squamous</term>
<term>Squamous cell carcinoma</term>
<term>Subclinical disease</term>
<term>Surg</term>
<term>Surgery</term>
<term>Surgical</term>
<term>Surgical exposure</term>
<term>Surgical margins</term>
<term>Surgical resection</term>
<term>Systemic chemotherapy</term>
<term>Target volume</term>
<term>Therapy</term>
<term>Tongue base</term>
<term>Tor</term>
<term>Toxicity</term>
<term>Transoral</term>
<term>Transoral laser microsurgery</term>
<term>Transoral resection</term>
<term>Transoral resections</term>
<term>Transoral surgery</term>
<term>Trial design</term>
<term>Uninvolved neck</term>
<term>Untreated</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Adjuvant</term>
<term>Cancer</term>
<term>Chirurgie</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Recent advances now permit resection of many pharyngeal tumors through the open mouth, an approach that can greatly reduce the morbidity of surgical exposure. These transoral techniques are being rapidly adopted by the surgical community and hold considerable promise. On November 6–7, 2011, the National Cancer Institute sponsored a Clinical Trials Planning Meeting to address how to further investigate the use of transoral surgery, both in the good prognosis human papillomavirus (HPV)–initiated oropharyngeal cancers, and in those with HPV‐unrelated disease. The proceedings of this meeting are summarized. © 2012 Wiley Periodicals, Inc. Head Neck, 2012</div>
</front>
</TEI>
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<list>
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<li>Canada</li>
<li>Géorgie (pays)</li>
<li>États-Unis</li>
</country>
<region>
<li>Caroline du Nord</li>
<li>Maryland</li>
<li>Massachusetts</li>
<li>Michigan</li>
<li>Minnesota</li>
<li>Missouri (État)</li>
<li>Ohio</li>
<li>Ontario</li>
<li>Pennsylvanie</li>
<li>Texas</li>
<li>Washington (État)</li>
<li>État de New York</li>
</region>
<settlement>
<li>Toronto</li>
</settlement>
<orgName>
<li>Université de Toronto</li>
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<name sortKey="Adelstein, David J" sort="Adelstein, David J" uniqKey="Adelstein D" first="David J." last="Adelstein">David J. Adelstein</name>
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<name sortKey="Adelstein, David J" sort="Adelstein, David J" uniqKey="Adelstein D" first="David J." last="Adelstein">David J. Adelstein</name>
<name sortKey="Bekelman, Justin E" sort="Bekelman, Justin E" uniqKey="Bekelman J" first="Justin E." last="Bekelman">Justin E. Bekelman</name>
<name sortKey="Brizel, David M" sort="Brizel, David M" uniqKey="Brizel D" first="David M." last="Brizel">David M. Brizel</name>
<name sortKey="Carey, Thomas E" sort="Carey, Thomas E" uniqKey="Carey T" first="Thomas E." last="Carey">Thomas E. Carey</name>
<name sortKey="Chepeha, Douglas B" sort="Chepeha, Douglas B" uniqKey="Chepeha D" first="Douglas B." last="Chepeha">Douglas B. Chepeha</name>
<name sortKey="Ferris, Robert L" sort="Ferris, Robert L" uniqKey="Ferris R" first="Robert L." last="Ferris">Robert L. Ferris</name>
<name sortKey="Forastiere, Arlene" sort="Forastiere, Arlene" uniqKey="Forastiere A" first="Arlene" last="Forastiere">Arlene Forastiere</name>
<name sortKey="Genden, Eric M" sort="Genden, Eric M" uniqKey="Genden E" first="Eric M." last="Genden">Eric M. Genden</name>
<name sortKey="Haughey, Bruce H" sort="Haughey, Bruce H" uniqKey="Haughey B" first="Bruce H." last="Haughey">Bruce H. Haughey</name>
<name sortKey="Holsinger, F Christopher" sort="Holsinger, F Christopher" uniqKey="Holsinger F" first="F. Christopher" last="Holsinger">F. Christopher Holsinger</name>
<name sortKey="Konski, Andre A" sort="Konski, Andre A" uniqKey="Konski A" first="Andre A." last="Konski">Andre A. Konski</name>
<name sortKey="Lowe, Val" sort="Lowe, Val" uniqKey="Lowe V" first="Val" last="Lowe">Val Lowe</name>
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<name sortKey="Manola, Judith" sort="Manola, Judith" uniqKey="Manola J" first="Judith" last="Manola">Judith Manola</name>
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<name sortKey="Movsas, Benjamin" sort="Movsas, Benjamin" uniqKey="Movsas B" first="Benjamin" last="Movsas">Benjamin Movsas</name>
<name sortKey="Quon, Harry" sort="Quon, Harry" uniqKey="Quon H" first="Harry" last="Quon">Harry Quon</name>
<name sortKey="Ramsey, Scott" sort="Ramsey, Scott" uniqKey="Ramsey S" first="Scott" last="Ramsey">Scott Ramsey</name>
<name sortKey="Ridge, John A" sort="Ridge, John A" uniqKey="Ridge J" first="John A." last="Ridge">John A. Ridge</name>
<name sortKey="Schuller, David E" sort="Schuller, David E" uniqKey="Schuller D" first="David E." last="Schuller">David E. Schuller</name>
<name sortKey="Ullmann, Claudio Dansky" sort="Ullmann, Claudio Dansky" uniqKey="Ullmann C" first="Claudio Dansky" last="Ullmann">Claudio Dansky Ullmann</name>
<name sortKey="Weber, Randal S" sort="Weber, Randal S" uniqKey="Weber R" first="Randal S." last="Weber">Randal S. Weber</name>
<name sortKey="Weinstein, Gregory S" sort="Weinstein, Gregory S" uniqKey="Weinstein G" first="Gregory S." last="Weinstein">Gregory S. Weinstein</name>
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<name sortKey="Beitler, Jonathan J" sort="Beitler, Jonathan J" uniqKey="Beitler J" first="Jonathan J." last="Beitler">Jonathan J. Beitler</name>
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